Terpenic fraction of Pterodon pubescens inhibits NF-kB and ERK 1/2 activation and deregulates gene expression in leukemia cells
نویسندگان
چکیده
Monica Farah Pereira 1 , E-mail: [email protected] Thiago Martino 1 , E-mail: [email protected], Sergio Ranto Dalmau 1 , E-mail: [email protected] (in memorium) Márcia Cristina Paes 1 , E-mail: [email protected] Christina Barja-Fidalgo 2 , E-mail: [email protected] Rodolpho Mattos Albano 1 , E-mail: [email protected] Marsen Garcia Pinto Coelho 1 , E-mail: [email protected] Kátia Costa de Carvalho Sabino 1 * , E-mail: [email protected]
منابع مشابه
Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein Kinase 1/2 activation and deregulates gene expression in leukemia cells
BACKGROUND Plant derived compounds have been shown to be important sources of several anti-cancer agents. As cell cycle deregulation and tumor growth are intimately linked, the discovery of new substances targeting events in this biochemical pathway would be of great value. The anti-leukemic effect of an ethanolic extract of Pterodon pubescens seeds (EEPp) has been previously demonstrated and n...
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